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Alderley Park Conference Centre, Alderley Edge, Macclesfield SK10 4TG   Safety risks are a major cause of attrition in drug discovery and development. A well designed and delivered toxicology package together with prompt and robust problem solving can make the difference between success and failure. With advances in novel in vitro and in silico methodologies along with the greater understanding of the underlying mechanisms and biomarkers, discovery toxicology has emerged as a fundamental aspect of early stage R&D and is…