NC3Rs workshop – ‘Applying exposure science to increase the utility of non-animal data in efficacy and safety testing’

Event Date: February 15th 08:02 - 16th 17:02 2017


In collaboration with Unilever, the NC3Rs is jointly hosting a two-day workshop entitled ‘Applying exposure science to increase the utility of non-animal data in efficacy and safety testing’ which will be held in central London on 15-16 February 2017.

This will bring together academic and industry researchers from multiple disciplines to share their knowledge and experiences in applying exposure-driven approaches to increase the utility of in vitro and in silico data for decision-making, efficacy and safety assessment. Greater incorporation of exposure considerations promises to increase the relevance of these models to improve safety assessment processes and reduce and refine the reliance on animal models.

The workshop will be attended by expert scientists from academia, government and regulatory agencies and the (agro)chemicals, consumer products, and pharmaceutical industries.

The key objectives of the workshop are to:


  • Increase awareness and build confidence in the application of exposure-driven approaches to support decision-making based on data from non-animal approaches across sectors;
  • Build a community of scientists working in the area of exposure-driven safety assessment;
  • Identify gaps and challenge areas that need to be addressed to advance the application of exposure science capability;
  • Develop and publish guidance to facilitate the use and wider acceptance of exposure-driven non-animal approaches to inform and improve safety and efficacy decision-making.


Confirmed speakers include:


  • Dr Roman Ashauer, University of York, UK
  • Professor Steven Charlton, University of Nottingham, UK
  • Dr Ian Cotgreave, Swetox, Sweden
  • Dr Iain Gardner, Certara/The SimCyp Consortium, UK
  • Professor Beate Escher, UFZ, Germany
  • Professor Gareth Jenkins, Swansea University, UK
  • Dr Nicole Kleinstreuer, NICEATM, USA
  • Professor Nynke Kramer, Utrecht University, Netherlands
  • Professor Philipp Mayer, Technical University of Denmark (DTU), Denmark
  • Dr Bette Meek, University of Ottawa, Canada
  • Dr Alicia Paini, European Commission Joint Research Centre
  • Dr Cecilie Rendal, Unilever, UK
  • Dr Steve Webb, University of Liverpool, UK


Attendance is free, but registration is essential. The closing date for registration is 09 January 2017.

Delegates are encouraged to submit poster abstracts on a topic relevant to the theme of the meeting and highlighting the potential 3Rs benefits. To present a poster, please complete the abstract submission form and submit via the registration site by 06 January 2017.

Please share this information with any colleagues or contacts you think may be interested in attending.