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Professor Brian Lake

Brian Lake obtained a BSc in Biochemistry from the University of Surrey and then under the guidance of Professor D.V. Parke obtained a PhD in the field of induction of hepatic and extrahepatic xenobiotic metabolising enzymes. He also holds a DSc from the University of Surrey and is a Fellow of the British Toxicology Society. Brian Lake worked at BIBRA International for over 30 years and subsequently was head of the LFR Molecular Sciences Department. He also holds the position of Visiting Professor in the Faculty of Health and Medical Sciences at the University of Surrey. During his career he has been involved in a wide range of multi-disciplinary research and contract projects. His research fields and expertise are broadly in the areas of the metabolism and toxicity of xenobiotics in mammalian systems. Particular interests include xenobiotic metabolism and the induction of xenobiotic metabolising enzymes; the development of in vitro systems for predicting xenobiotic metabolism and toxicity; modes of action of non-genotoxic carcinogenesis and the extrapolation of animal data to human hazard assessment. Brian Lake has published over 240 scientific papers and has acted as a consultant to various international companies. He is currently a member of the Committee on Toxicity of Chemicals in Food, Consumer Products and the Environment (COT).